Medical experimentation on human subjects as an issue of bioethics

Most of them believe that the Earth is only 6 thousand years old, that the Universe was created in 6 days by God.

Medical experimentation on human subjects as an issue of bioethics

References and Further Reading 1. Metaphysics Traditionally, metaphysics pertains to the analysis of objects or events and the forces or factors causing or impinging upon them. One branch of metaphysics, denoted ontology, investigates problems and questions concerning the nature and existence of objects or events and their associated forces or factors.

Another branch of metaphysics involves the examination of presuppositions that inform a given ontology. For philosophy of medicine, the most controversial debate centers around the presuppositions of reductionism and holism.

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In addition, the debate between realism and antirealism has important traction within the field. Holism The reductionism-holism debate enjoys a lively history, especially from the middle to the latter part of the twentieth century.

Reductionism, broadly construed, is the diminution of complex objects or events to their component parts. In other words, the properties of the whole are simply the addition or summation of the properties of the individual parts.

Such reductionism is often called metaphysical or ontological reductionism to distinguish it from methodological or epistemological reductionism.


Methodological reductionism refers to the investigation of complex objects and events and their associated forces or factors by using technology that isolates and analyzes individual components only. Epistemological reductionism involves the explanation of complex objects and events and their associated forces or factors in terms of their individual components only.

Life scientists often sort these parts into a descending hierarchy. Jan Smuts introduced the term in the early part of the twentieth century, especially with respect to biological evolution, to account for living processes—without the need for immaterial components.

The relevance of the reductionism-holism debate pertains to both medical knowledge and practice. Reductionism influences not only how a biomedical scientist investigates and explains disease, but also how a clinician diagnoses and treats it. For example, if a biomedical researcher believes that the underlying cause of a mental disease is dysfunction in brain processes or mechanisms, especially at the molecular level, then that disease is often investigated exclusively at that level.

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In turn, a clinician classifies mental diseases in terms of brain processes or mechanisms at the molecular level, such as depletion in levels of the neurotransmitter serotonin. Subsequently, the disease is treated pharmacologically by prescribing drugs to elevate the low levels of the neurotransmitter in the depressed brain to levels considered normal within the non-depressed brain.

Although the assumption of reductionism produces a detailed understanding of diseases in molecular or mechanistic terms, many clinicians and patients are dissatisfied with the assumption. Rather than simply treating the disease, such information is vital for treating patients with chronic cases.

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Rather than striving exclusively for restoration of the patient to a pre-diseased state, the clinician assists the patient in redefining what the illness means for their life. Antirealism Realism is the philosophical notion that observable objects and events are actual objects and events, independent of the person observing them.

In other words, since it exists outside the minds of those observing it, reality does not depend on conceptual structures or linguistic formulations. Proponents of realism also espouse that even unobservable objects and events, like subatomic particles, exist.

Historically, realists believe that universals—abstractions of objects and events—are separate from the mind cognizing them. For example, terms like bacteria and cell denote real objects in the natural world, which exist apart from the human minds trying to examine and understand them.

Furthermore, scientific investigations into natural objects like bacteria and cells yield true accounts of these objects. Anti-realism, on the other hand, is the philosophical notion that observable objects and events are not actual objects and events as observed by a person but rather they are dependent upon the person observing them.

In other words, these objects and events are mind-dependent—not mind-independent. Anti-realists deny the existence of objects and events apart from the mind cognizing them.Bioethics, Medical, Health, drug list, medical reference, Sports Medicine, Exercise, Strength Training, Cyber-Abuse, Cyberbulling, School Crisis Guide, digital.

The Belmont Report was written by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research.

Medical experimentation on human subjects as an issue of bioethics

The Commission, created as a result of the National Research Act of , was charged with identifying the basic ethical principles that should underlie the conduct of biomedical and behavioral research involving human subjects and developing guidelines to.

Unethical human experimentation in the United States describes numerous experiments performed on human test subjects in the United States that have been considered unethical, and were often performed illegally, without the knowledge, consent, or informed consent of the test tests have occurred throughout American history, but particularly in the 20th century.

Ethical and legal issues in research involving human subjects: do you want a piece of me?

even if the specimen is identified only by a code. 28 Other bioethics scholars go it is necessary to consider the confidentiality implications of collecting and storing tissue to be used in the research context.

In the USA, medical confidentiality. Jing-Bao Nie is an Associate Professor at the Bioethics Centre, Dunedin School of Medicine, University of Otago, New Zealand, and honorary adjunct professor at Hunan Normal and Peking Universities, China.

A critical examination of the ethics of medical experimentation on human subjects, focusing on the medical experiments conducted on human subjects by the doctors in Nazi Germany, as well as, in post-war U.S.

may contribute to a .

Ethical and legal issues in research involving human subjects: do you want a piece of me?